Pith Helmet: extended prefs and ad blocking. Beta support for Safari 3. $10
Saft: extended prefs and ad blocking. Beta support for Safari 3. $12.
Ad blocking and Flash animation blocking are built in. <3 Camino. Free.
Adblock & Flashblock: Flashblock gets everything that Adblock doesn't. Free.
Er, I have no idea what people still using IE do to block ads. Sling me a link and I will edit.
My personal corollary to this practice: I pay for services I use often. My LJ account is paid. I pay for Salon. I pay for Pandora. And so on. But I do so love never having to see this image. For instance.